Enzymology in Drug Discovery

Enzymes are the proteins in the drug design that act as drug targets for the diseases in the process of drug discovery and development. There are number of drug targets involved in the designing of the drug.

Drug target as a nucleic acid or a protein (e.g. an enzyme, a receptor) whose activity can be modified by a drug. The drug can be a small-molecular-weight chemical compound or a biological, such as an antibody or a recombinant protein. The drug target should have been shown to be effective/mechanistically involved in the disease by relevant in vitro or in vivo models.