2^nd International Conference on Enzymology and Molecular Biology March 20-21, 2017 Rome, Italy

Dr. Alexandros Makriyannis, Ph.D. is the George D. Behrakis Endowed Chair in Pharmaceutical Biotechnology at Northeastern University. Dr. Makriyannis has spent the two decades inventing and applying chemical, biochemical and biophysical approaches to study the endocannabinoid signaling system and exploring its therapeutic potential. In 2005, he established Northeastern University’s Center for Drug Discovery. Dr. Makriyannis is a Professor of Chemistry, Chemical Biology and Pharmaceutical Sciences and the Director of the Center for Drug Discovery at Northeastern University. He served as the Head of Scientific Advisory Board at CannaVest Laboratories, LLC since June 2014. Dr. Makriyannis serves as a Member of Advisory Board at CV Sciences, Inc. He served as a Member of Scientific Advisory Board at CannaVest Laboratories, LLC. Through his multidisciplinary work encompassing both chemistry and biology, he has been a pioneer in chemical biology even before this designation was coined. He was among the first to define the biochemical pathways of endocannabinoids within the human endocannabinoid system (ECS).

Cannabinergic agents; drugs of abuse; structure and function of G-protein coupled receptors and enzymes; enzyme inhibitors; drug-membrane interactions; neurosteroids; endocannabinoid biomarkers

Henry M Sobell has completed his studies at Brooklyn Technical High School (1948-1952), Columbia College (1952-1956) and the University of Virginia, School of Medicine (1956-1960) in Brooklyn New York. Instead of practicing Clinical Medicine, he then went to the Massachusetts Institute of Technology, Cambridge to join Professor Alexander Rich in the Department of Biology (1960-1965) as a Helen Hay Whitney Postdoctoral fellow; he learned the technique of single Crystal X- Ray Analysis. He then joined the Chemistry Department at the University of Rochester and was then jointly appointed to the Department of Biophysics School of Medicine and Dentistry becoming a full Professor in both departments (1965-1993). He is now retired and living in New York, USA.

Understanding of the structure and physical properties of DNA.

Theo Hofmann is an emeritus professor in the University of Toronto, ON, Canada in the department of Biochemistry.

Protein Purification, Enzymology, Chromatography, Enzyme Activity, DNA cloning, Making Mutants

Dr. Amnon Kohen is a Professor of Chemistry and of Molecular and Cellular Biology. Amnon received his B.Sc. degree in Chemistry in 1989 from the Hebrew University in Jerusalem and Doctor of Sciences (D.Sc.) degree in 1994 from Technion-Israel Institute of Technology. After that he was a postdoctorial fellow with Prof. Judith Klinman at the University of California at Berkeley. In 1999, he moved to the University of Iowa and his main interest is mechanistic enzymology and bioorganic chemistry. His research focuses on the relationship between enzyme structure, dynamics, and catalysis, as well as the use of isotope effects in studying enzymes. His research group also pursues medical and technological applications of biological catalysts, and since 2013 he is the Director of the Iowa Graduate Program in Biotechnology.

Mechanistic Enzymology and Bioorganic Chemistry.

David Mousdale , Ph, D., has done his graduation, M.A. from University of Oxford and then completed his ph. D., from University of Cambridge in Plant Biochemistry in the year 1974-1978.In 1991 he became the technical director of Bioflux Ltd. and in 1997 Managing Director of Biopep Ltd.. Currently he is holding the position of Managing Director of Beocarta Ltd. beocarta is a specialist provider of metabolic analysis to the fermentation and biotech industries and has worked with clients in the united States, Japan, Korea, Europe and India.

Industrial fermentation processes for enzymes & Biofuels and Biomass Resources

Prof. Jennifer Littlechild, Ph.D., serves as a Member of Scientific Advisory Panel at Aquapharm Biodiscovery Limited. Prof. Littlechild supervises Aquapharm's BBSRC industrial case studentship on biocatalysis and Enzyme Discovery. She has been a Member of Scientific Advisory Board at CO2 Solutions Inc., since June 12, 2014. Prof. Littlechild serves as Director of Exeter Biocatalysis Centre, School of Biosciences, University of Exeter. Prof. Littlechild is College of Life and Environmental Sciences, University of Exeter. Prof. Littlechild is a Professor of Biological Chemistry at the University of Exeter. Prof. Littlechild is a world renown specialist in extremophile enzymes and their application in industrial processes. Prof. Littlechild’s research interests cover molecular genetics (site-directed mutagenesis and gene isolation and cloning), protein purification and characterization, and structural analysis by NMR, X-ray crystallography and molecular modelling of new enzymes for biotransformation and drug design.

Biological Chemistry, Cellular & Chemical Biology, Biophysics, Physical and Organic Chemistry

Lene Lange is a Professor at Center for BioProcess Engineering, DTU Chemical Engineering, Denmark. She has held research director positions in both industry and academia; has hereby acquired extensive experience from all parts of the knowledge-value-chain: research, technology, innovation, patenting, environmental impact assessment, product development, knowledge management, business models, and commercialization. Current advisory positions: The Danish National Bioeconomy Panel, The Nordic Bioeconomy Panel, Scientific Committee for the BBI JU, Expert Group for the Review of the Bioeconomy and its Actionplan, IAB BIOTEC Thailand.

Discovery of novel enzymes for improved biomass conversion and biorefinery processes, with specific focus on generating value from agroindustrial side streams and waste products. Development of the new enzyme discovery platform, PPR, a non-alignment based sequence analysis method, predicting function directly from sequence. Using PPR analysis, combined with MS, phylogenetic analysis and activity screening for increased understanding of Nature´s enzymatic hot spots.

Takashi Yonetani has received his BS (Biology) in 1952 and PhD (Biochemistry) in 1960 from Osaka University and postdoctoral research training at Medical Nobel Institute, Karolinksa Institute in 1961-64. He joined the faculty of Perelman School of Medicine in 1964 and has been Professor of Biochemistry & Biophysics since 1968. He has published more than 300 peer-articles on structure-functions of oxidation-reduction enzymes and proteins, particularly heme enzymes like cytochrome c oxidase and cytochrome c peroxidase and hemoproteins such as myoglobin and hemoglobin.

Biochemistry,Biophysics, Medicine, Ligand binding dynamics in myoglobin, Allosteric mechanism in hemoglobin, The mechanism of action of cytochrome c peroxidase.

Giuseppe Manfroni graduated with full marks in Pharmaceutical Chemistry and Technology (March 2001) and received his PhD in Medicinal Chemistry (February 2006) from the University of Perugia (Italy). From 2006 to 2008 he worked as a postdoctoral researcher at the University of Perugia. From 2008 to date he is Assistant Professor at the Department of Pharmaceutical Sciences and he is a lecturer in Pharmaceutical Analysis. He spent short periods as a visiting PhD student at Rega Institute for Medical Research (Leuven, Belgium) and at the Molecular Modelling Laboratory (University of Perugia) under the supervision of Prof. Johan Neyts and Prof. Gabriele Cruciani, respectively. He is the author of 40 papers, and his research is mainly focused on Medicinal Chemistry of antiviral (HIV, HCV, and flavivirus), antitumor, and anti-inflammatory (p38 inhibitors) agents.

Medicinal Chemistry of antiviral (HIV, HCV, and flavivirus), antitumor, and anti-inflammatory (p38 inhibitors) agents.

Simone Weyand did her Postdoc in the year 2007-2012 from Imperial College London and Postdoc Research from University of Cambridge in 2012. Currently he is the Group Leader of Biochemistry Deptt in Sir Henry Dale Fellowships-University of Cambridge.

Membrane Protein Structure, Function and Cellular Activities

Dr. Carla Emiliani is a Professor of Biochemistry in the Department of Chemistry, Biology and Biotechnology, University of Perugia, Italy. She did her Ph.D. from the University of Perugia in Biochemistry and published many research articles in the field of therapeutic delivery of enzymes, gene expression and more related subjects.

Affinity Chromatography, Nanotechnology, Cell Based Assays, Assay, Development, In Vitro Assays, Nanobiology, Stem Cells, Nanoparticles Drug Delivery, Proteins, Cell Differentiation, Platelet Activation, Biotechnology, Lysosome, Western Blot, Biomaterials, Regenerative Medicine, Cell Culture, In Vitro Cell Culture, PCR, Neuroscience, Nanomedicine, Electrophoresis

Valentina Emilia Balas holds a Ph.D, in Apllied Electronics and Telecommunications from University “Politechnica”din Timisoara in the year 1995-2003. In the year 1984 she was the engineer –R&D for Railway Cars from ARAD- CCSITVA. Currently she is the professor of Aurel Vlaicu University of Arad.

Image Processing, Artificial Intelligence, Mat lab, R&D.