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Mamuka Kvaratskhelia


Mamuka Kvaratskhelia

University of Colorado School of Medicine, USA

Biography

Mamuka Kvaratskhelia began his independent research career at the Ohio State University in 2003 and has focused on better understanding of the structure and function of HIV-1 integrase as a therapeutic target. He has recently (2017) moved to University of Colorado Denver as a Professor of Medicine (Infectious Diseases) to further extend his studies on HIV-1 integrase. By employing innovative biochemical, biophysical, structural biology, molecular biology and virology approaches, his research team has made many important contributions to the field, which include the discovery of second, non-catalytic role of integrase in HIV-1 biology and elucidating the mode of action of ALLINIs.

Abstract

Abstract : The dual role of integrase in HIV-1 replication