Giuseppe Manfroni
Università degli Studi di Perugia, Italy
Biography
Giuseppe Manfroni has graduated in Pharmaceutical Chemistry and Technology (2001) and received his PhD in Medicinal Chemistry (2006) from the University of Perugia (Italy). From 2006 to 2008, he worked as a Post-doctoral Researcher at the University of Perugia. From 2008 to date he is an Assistant Professor in the Department of Pharmaceutical Sciences and is a Lecturer in Pharmaceutical Analysis. He has spent short periods as a Visiting PhD Student at Rega Institute for Medical Research (Leuven, Belgium) and at the Molecular Modeling Laboratory (University of Perugia) under the supervision of Professor Johan Neyts and Professor Gabriele Cruciani, respectively. He is the author of 40 papers, and his research is mainly focused on Medicinal Chemistry of antiviral (HIV, HCV, and Flavivirus), antitumor, and anti-inflammatory (p38 inhibitors) agents. He is an expert on the synthesis of heterocyclic compounds and microwave assisted synthesis.
Abstract
Abstract : Inhibition of the RNA-dependent RNA polymerasic activity of Flavivirus NS5 by heterocyclic compounds